Breast Cancer
Breast cancer is the most common malignancy in
women and the second leading cause of cancer death
in women, after lung cancer.
The breast is a gland designed to make milk. The
lobules in the breast make the milk, which then
drains through the ducts to the nipple.
Anatomically, the breast is composed of the
nipple, areola, lactating sinuses, ducts and the
lobular units.
The cells in breasts usually grow and rest in
cycles. The periods of growth and rest in each
cell are controlled by genes in the cell's
nucleus. When genes develop an abnormality, they
sometimes lose their ability to control the cycle
of cell growth and rest. Breast cancer is the
uncontrolled growth of breast cells.
Breast cancer can be caused by either hormonal or
genetic factors.
There are several types of breast cancer depending
on the site of origin and microscopic features:
ductal, lobular, medullary, papillary and colloid
carcinoma.
Early symptoms of breast cancer may be
undetectable. However, as the cancer grows it can
cause changes that women should watch for:
· A lump or thickening in or near the breast or
the underarm area.
· A change in the size or shape of the breast.
· Discharge from the nipple.
· A change in the color or feel of the skin of
the breast, areola, or nipple (dimpled, puckered,
or scaly).
Breast cancer can spread locally through the
Lymphatic system to the draining lymph nodes
nearby and distally through blood to the brain,
lung, bone and liver.
Breast cancer can be diagnosed by self examination
of the breast, mammography, and biopsy.
Breast cancer can be treated by surgery, hormonal
therapy, chemotherapy, or some combination of
these treatments.
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